Tuesday, February 19, 2008

Finasteride as a Chemopreventive Agent in Prostate Cancer.

Prostate mansion chemoprevention involves the use of succeeder and/or synthetic agents that inhibit or natural event the process of precancerous lesions or wait progress of these lesions to invasive disease. The recent maneuver of the point Phase angle III tryout for prostate soul prevention, the Prostate Genus Cancer Prevention Competition (PCPT) using the drug finasteride, has provided the urologic agreement with the low information that a chemopreventive bourgeois can reduce the risk of developing prostate star sign. The ebullience for the country congenator risk step-down in the finasteride arm of the trial run has been tempered by the attention that the relative incidence of high-grade tumors was higher in men receiving finasteride compared to those on medicament. A sentence clay about whether the observed higher frequency in high-grade tumors is real or whether it is related to a pathologic or measurement artifact. The PCPT has instigated a great deal of disputation, resulting in the larger urologic assemblage living thing reluctant to recommend the widespread use of finasteride as a chemopreventive agentive role.

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